1. image: Download

    【Donkey Dragged On Brazil Highway】 
In a vicious act of animal cruelty a man tied a donkey to his car and dragged him by for more than 3 kilometers. The incident occurred in the village Tres Barras, in the municipality of Graccho Cardos, Sergipe region, Brazil.

The perpetrator was identified as 67-year-old Celso Ferreira, who claims he tied and abused the donkey just for fun. The donkey could not survive all the heavy injuries it sustained and eventually died. Although local police immediately arrested the man, it appears he is very well connected, as the mayor inexplicably ordered his release.
    【Donkey Dragged On Brazil Highway】 
    In a vicious act of animal cruelty a man tied a donkey to his car and dragged him by for more than 3 kilometers. The incident occurred in the village Tres Barras, in the municipality of Graccho Cardos, Sergipe region, Brazil.
    The perpetrator was identified as 67-year-old Celso Ferreira, who claims he tied and abused the donkey just for fun. The donkey could not survive all the heavy injuries it sustained and eventually died. Although local police immediately arrested the man, it appears he is very well connected, as the mayor inexplicably ordered his release.

    (Source: facebook.com)

     
  2. 【New Slave Wanted】Nathan Needs A Forever Home
Domestic Short Hair-black and white • Adult • Male • LargeBrown County Humane Society Nashville, INHow can you resist that face? With his retro haircut (doesn’t he remind you of the Beatles?), Nathan has all the personality in the world. He’s a real sweetheart, super friendly and he loves to greet everyone who comes by. Nathan loves to walk around and rub against your legs, asking for attention. He’s also very fond of his food. He’s just a generally happy guy.
Brown County Humane Society|*Official Website: http://www.bchumane.org/*Google+ Website: https://plus.google.com/115998297882785368182/

    New Slave WantedNathan Needs A Forever Home

    Domestic Short Hair-black and white • Adult • Male • Large
    Brown County Humane Society Nashville, IN

    How can you resist that face? With his retro haircut (doesn’t he remind you of the Beatles?), Nathan has all the personality in the world. He’s a real sweetheart, super friendly and he loves to greet everyone who comes by. Nathan loves to walk around and rub against your legs, asking for attention. He’s also very fond of his food. He’s just a generally happy guy.

    Brown County Humane Society|
    *Official Website: http://www.bchumane.org/
    *Google+ Website: https://plus.google.com/115998297882785368182/

     
  3. Hire a blind to save your business running electricity cost….  LOL

     
  4. Horrible!
    Hard to believe those pretty guys are the same one in comparing photos!

    15 Shocking Before-After Pics Showing Effects of Drug Abuse

    BY  / ON JANUARY 13, 2014 AT 9:24 AM

    These shocking before and after pics show the negative effects of drug addiction on the human face.

    Released with the hope that kids will think twice about ever touching drugs, these pictures show how addicts have lost teeth and scratched their skin to the bone.

    These pics show the first arrest of a drug and a pic taken in some cases just a few months later.

    They have been assembled by the Multnomah County Sheriff’s Office in Oregon.

     
  5. 【Like Clicking Activity!】
Could any body do me a favor over here?This little pretty left School because she was being called Ugly.Please link the following site to give your Like click for her!Guys! Like this photo to prove that she is not Ugly.
Like= Gorgeous/Beautiful♥ Ignore= Ugly:(
Link Site: https://plus.google.com/110736170608349824780/posts/VPMKEg1BYVZ

    【Like Clicking Activity!】

    Could any body do me a favor over here?

    This little pretty left School because she was being called Ugly.
    Please link the following site to give your Like click for her!

    Guys! Like this photo to prove that she is not Ugly.

    Like= Gorgeous/Beautiful♥ Ignore= Ugly:(

    Link Site: https://plus.google.com/110736170608349824780/posts/VPMKEg1BYVZ

     
  6. I do really think, our forefathers must be very naughty!

    »Photo Source: https://www.facebook.com/SarahJezebelDeva

    (Source: peta.gov)

     
  7. image: Download

    Very horrible, next time playing on the beach, you got to notice about this, it is really a problem.Shark photobomb? Family photo captures big fish lurking just feet from family
Can there be such thing as a shark photobomb?
That’s what many are calling an eerie and eye-catching photo inadvertently snapped by a California mother that appears to show a large shark, or maybe a dolphin, swimming near her two children.
"It was quite a shock to see” the photo, June Emerson told KTLA about her photo, which captured the outline of a large fish swimming underneath a breaking wave close to the shore on Manhattan Beach.
“Many local surfers and lifeguards have seen this and believe it to be a shark,” Emerson said. “Of course, I told my kids it was dolphin, as we live at the beach and are in the waters here almost daily.”
Emerson said her 12-year-old twins were also unaware of the fish swimming so close to them as they played in the waters off the popular beach on Friday.
Emerson posted the picture to her Facebook page and said she has received thousands of comments from people, nearly all of whom are convinced that the creature in the image is a shark, possibly even a great white, which are relatively common to the area.
Still, other observers say it’s impossible to tell without a more detailed image. For example, the shape of the fins and tail could in fact belong to those of a dolphin. Nonetheless, shark sightings in the area have become more frequent in recent years. So, it’s well within the realm of possibility that Emerson captured a large shark close to the shore.
Back in November, paddleboarders captured video of a great white in the same area. That video was taken just 50 yards from the shore. And while most people would be terrified by the thought of sharing personal space with what is arguably the Earth’s deadliest predator, the California Department of Fish and Wildlife actually issued a warning for people to leave the sharks alone – for the protection of the sharks.
For her part, Emerson said she’s more than happy to just go on pretending that it was nothing more than a friendly dolphin passing by during an otherwise pristine day.
“Another beautiful day at the beach,” Emerson wrote on her Facebook page. “Big waves and apparently Big Fish! (Look into wave to right of Quinn Emerson, who’s out catching a few!) – Manhattan Beach, California.”

    Very horrible, next time playing on the beach, you got to notice about this, it is really a problem.

    Shark photobomb? Family photo captures big fish lurking just feet from family

    Can there be such thing as a shark photobomb?

    That’s what many are calling an eerie and eye-catching photo inadvertently snapped by a California mother that appears to show a large shark, or maybe a dolphin, swimming near her two children.

    "It was quite a shock to see” the photo, June Emerson told KTLA about her photo, which captured the outline of a large fish swimming underneath a breaking wave close to the shore on Manhattan Beach.

    “Many local surfers and lifeguards have seen this and believe it to be a shark,” Emerson said. “Of course, I told my kids it was dolphin, as we live at the beach and are in the waters here almost daily.”

    Emerson said her 12-year-old twins were also unaware of the fish swimming so close to them as they played in the waters off the popular beach on Friday.

    Emerson posted the picture to her Facebook page and said she has received thousands of comments from people, nearly all of whom are convinced that the creature in the image is a shark, possibly even a great white, which are relatively common to the area.

    Still, other observers say it’s impossible to tell without a more detailed image. For example, the shape of the fins and tail could in fact belong to those of a dolphin. Nonetheless, shark sightings in the area have become more frequent in recent years. So, it’s well within the realm of possibility that Emerson captured a large shark close to the shore.

    Back in November, paddleboarders captured video of a great white in the same area. That video was taken just 50 yards from the shore. And while most people would be terrified by the thought of sharing personal space with what is arguably the Earth’s deadliest predator, the California Department of Fish and Wildlife actually issued a warning for people to leave the sharks alone – for the protection of the sharks.

    For her part, Emerson said she’s more than happy to just go on pretending that it was nothing more than a friendly dolphin passing by during an otherwise pristine day.

    “Another beautiful day at the beach,” Emerson wrote on her Facebook page. “Big waves and apparently Big Fish! (Look into wave to right of Quinn Emerson, who’s out catching a few!) – Manhattan Beach, California.”

     
  8. The Best 2013 Christmas Story Ever!

    Thousands of Christmas carolers have gathered to sing outside the home of a dying 8-year-old girl in West Reading, Pennsylvania. Delaney ‘Laney’ Brown was diagnosed with acute myeloid leukemia and, when doctors said she had only weeks to live, one of her final wishes was to hear Christmas carolers. Her family turned to Facebook for support and a ‘Christmas Caroling for Laney’ event was organized for Saturday night.

    And this little angel already dead in the Christmas day.

     
  9. image: Download

     Boy paralysed after tumour fights back to gain a black belt  A BOY left paralysed after a brain tumour has baffled doctors by making an unexpected recovery – and gaining a black belt in Taekwondo.
Daniel Kimmins, now 14, underwent emergency surgery days before his seventh birthday when doctors discovered the tumour.
After the operation at Bristol’s Frenchay Hospital, the youngster was left paralysed down the left side of his body and doctors warned him that it could be permanent.
But now Daniel, from Bath, Somerset, has fought against the odds to make a full recovery. He first took up the martial art when he was six – and within a year had earned his yellow belt.
But he had to give up his hobby after the tumour left him fighting for his life.
His mother Heidi, 47, said: “After his operation, Daniel could not move the left side of his body and he had lost the ability to speak. We were never given any hope and got the impression he would not recover from the tumour.
“But he has learnt to walk and talk all over again and he is able to do all of the things he did before – which makes me unbelievably proud of him.”
At first, Daniel found the Taekwondo a lot harder than he used to.
So he was over the moon to be rewarded with the black belt a few weeks ago.
He said: “It was just absolutely amazing.”

    Boy paralysed after tumour fights back to gain a black belt

    A BOY left paralysed after a brain tumour has baffled doctors by making an unexpected recovery – and gaining a black belt in Taekwondo.

    Daniel Kimmins, now 14, underwent emergency surgery days before his seventh birthday when doctors discovered the tumour.

    After the operation at Bristol’s Frenchay Hospital, the youngster was left paralysed down the left side of his body and doctors warned him that it could be permanent.

    But now Daniel, from Bath, Somerset, has fought against the odds to make a full recovery. He first took up the martial art when he was six – and within a year had earned his yellow belt.

    But he had to give up his hobby after the tumour left him fighting for his life.

    His mother Heidi, 47, said: “After his operation, Daniel could not move the left side of his body and he had lost the ability to speak. We were never given any hope and got the impression he would not recover from the tumour.

    “But he has learnt to walk and talk all over again and he is able to do all of the things he did before – which makes me unbelievably proud of him.”

    At first, Daniel found the Taekwondo a lot harder than he used to.

    So he was over the moon to be rewarded with the black belt a few weeks ago.

    He said: “It was just absolutely amazing.”

    (Source: express.co.uk)

     
  10. "Michelin guide" for Rome homeless published
 
ROME Thu Dec 19, 2013 10:21am EST
(Reuters) - Most guidebooks tell people where to go to spend money and eat well. This one tells poor people the best places to get a free meal and hot bath.
Rome’s Sant’ Egidio community, a Catholic group that has been nominated for the Nobel Peace Prize, unveiled its latest guidebook for the needy on Thursday, in a city hit hard by years of economic crisis.
The 2014 edition of the guide, which the Italian media have dubbed the “Michelin guide for the poor,” has a print run of 13,000 copies and offers advice to the growing number of homeless and needy in the Italian capital.
It is called “Rome, where to eat, sleep, wash” and styled like a tourist guidebook.
The new edition is 227 pages long and lists 68 soup kitchens, 42 shelters where the homeless can sleep, 16 places to wash, as well as where to access medical care and counseling.
The group said there were about 8,000 homeless people in Rome and that the number has grown by about 10 percent in recent years. Others have homes but need meals and social services.
In the past, the group has focused on helping the poor among Italy’s immigrant community.
"After six or seven years of economic crisis, the number of poor Italians has increased," said the Sant’ Egidio community’s president, Marco Impagliazzo.
On Monday, data from national statistics office Istat showed a third of people living in Italy risked poverty or social exclusion, compared with a European average of 24.8 percent. Just over 21 percent were not able to heat their homes adequately, up from 18 percent in 2011.
(Reporting By Philip Pullella; Editing by Rosalind Russell)

»Rome, where to eat, sleep, wash Here are the links of 1990~2009 editions, but you could enquiry about the 2013 or 2014 edition for charity demand.

    "Michelin guide" for Rome homeless published

    ROME Thu Dec 19, 2013 10:21am EST

    (Reuters) - Most guidebooks tell people where to go to spend money and eat well. This one tells poor people the best places to get a free meal and hot bath.

    Rome’s Sant’ Egidio community, a Catholic group that has been nominated for the Nobel Peace Prize, unveiled its latest guidebook for the needy on Thursday, in a city hit hard by years of economic crisis.

    The 2014 edition of the guide, which the Italian media have dubbed the “Michelin guide for the poor,” has a print run of 13,000 copies and offers advice to the growing number of homeless and needy in the Italian capital.

    It is called “Rome, where to eat, sleep, wash” and styled like a tourist guidebook.

    The new edition is 227 pages long and lists 68 soup kitchens, 42 shelters where the homeless can sleep, 16 places to wash, as well as where to access medical care and counseling.

    The group said there were about 8,000 homeless people in Rome and that the number has grown by about 10 percent in recent years. Others have homes but need meals and social services.

    In the past, the group has focused on helping the poor among Italy’s immigrant community.

    "After six or seven years of economic crisis, the number of poor Italians has increased," said the Sant’ Egidio community’s president, Marco Impagliazzo.

    On Monday, data from national statistics office Istat showed a third of people living in Italy risked poverty or social exclusion, compared with a European average of 24.8 percent. Just over 21 percent were not able to heat their homes adequately, up from 18 percent in 2011.

    (Reporting By Philip Pullella; Editing by Rosalind Russell)

    »Rome, where to eat, sleep, wash
    Here are the links of 1990~2009 editions, but you could enquiry about the 2013 or 2014 edition for charity demand.

     
  11. Just the same subject as former post, there’s do have something worth to remind you as soon as possible in this life.

    Keep your time, good luck, guys!

     
  12. This famous vision design just makes me feel totally alone and sad, every channel will finally goes to the end irretrievable.
Whatever construct your life will waste you the most, should I find much more stuffs to smooth the day, or just sad for what it is composed from?
We’ll all approach this point one day, but it will be benefit to remind yourself as early as possible, in this life.

    This famous vision design just makes me feel totally alone and sad, every channel will finally goes to the end irretrievable.

    Whatever construct your life will waste you the most, should I find much more stuffs to smooth the day, or just sad for what it is composed from?

    We’ll all approach this point one day, but it will be benefit to remind yourself as early as possible, in this life.

    (Source: youtu.be)

     
  13. You ought to know how your Angora clothes makes of, cruel enough.

    A PETA Asia undercover investigation reveals the cruelty behind the angora rabbit fur industry, please urge the Chinese government to ban the cruel live plucking of rabbits for angora fur: http://peta.vg/angora

    PETA Saves: http://features.peta.org/petasaves/
    PETA: http://PETA.org

    Subscribe: http://youtube.com/subscription_cente…
    Spanish version: http://youtu.be/ZXyR7fpQO5k
    Chinese version: http://youtu.be/UUSg348jraE
    German version: http://youtu.be/TIieBLmqixI 

    The website the meat industry doesn’t want you to see:http://meat.org
    How to go vegan: http://features.peta.org/how-to-go-ve…

    FAQs: http://www.peta.org/about/faq/default…

    (Source: PETA.org)

     
  14. My personal opinion is: If such kind of mosquito studies could goes another way, discovering the very plants which could easily plant surrounding our house or environments in order to reduce mosquitoes or bad insects, I think it will be helpful in some wild area, just like Africa.

    But there is also a problem: What if this could makes mosquitoes generate drug resistance?

    Targeting a Dual Detector of Skin and CO2 to Modify Mosquito Host Seeking

    Cell, Volume 155, Issue 6, 1365-1379, 5 December 2013
    Copyright © 2013 Elsevier Inc. All rights reserved.
    10.1016/j.cell.2013.11.013

    Authors: Genevieve M. Tauxe,Dyan MacWilliam,Sean Michael Boyle,Tom Guda,Anandasankar Ray

    • Highlights
    • Mosquito CO2 neurons (cpA) detect human skin odor and are important for attraction
    • In silico screen of >440k chemicals finds excellent agonists and antagonists of cpA
    • Blocking cpA activity abolishes attraction behavior toward human skin odor and CO2
    • Agonists that lure mosquitoes to traps represent safe affordable control

    Summary

    Female mosquitoes that transmit deadly diseases locate human hosts by detecting exhaled CO2 and skin odor. The identities of olfactory neurons and receptors required for attraction to skin odor remain a mystery. Here, we show that the CO2-sensitive olfactory neuron is also a sensitive detector of human skin odorants in both Aedes aegypti and Anopheles gambiae. We demonstrate that activity of this neuron is important for attraction to skin odor, establishing it as a key target for intervention. We screen ∼0.5 million compounds in silico and identify several CO2 receptor ligands, including an antagonist that reduces attraction to skin and an agonist that lures mosquitoes to traps as effectively as CO2. Analysis of the CO2 receptor ligand space provides a foundation for understanding mosquito host-seeking behavior and identifies odors that are potentially safe, pleasant, and affordable for use in a new generation of mosquito control strategies worldwide.

    Introduction

    Mosquitoes transmit deadly pathogens like malaria parasites, dengue viruses, and filarial worms to hundreds of millions of people every year. Female mosquitoes use two volatile cues to select and navigate toward hosts: exhaled CO2 and human skin odorants (Cardé and Gibson, 2010,Dekker and Cardé, 2011,Dekker et al., 2005,Gillies, 1980,Mboera et al., 2000). Host preference and host-seeking ability play pivotal roles in disease transmission and are targets for intervention.

    Female mosquitoes detect plumes of exhaled CO2 using a class of olfactory receptor neurons (ORNs) designated cpA. CpA neurons are housed in capitate peg(cp) sensilla on the maxillary palps and express the CO2 receptor, comprising three conserved members of the Gustatory receptor (Gr) gene family (designatedGr1, Gr2, and Gr3 in most mosquitoes or Gr22, Gr23, and Gr24 in A. gambiae) (Figure 1A) (Grant and O’Connell, 1996,Jones et al., 2007,Lu et al., 2007,Robertson and Kent, 2009,Syed and Leal, 2007). A host-seeking female will fly upwind when these neurons are activated, toward a CO2 source in a laboratory arena or to CO2-baited traps in the field (Cooperband and Cardé, 2006,Dekker et al., 2005,Healy and Copland, 1995,Lacey and Cardé, 2011,Xue et al., 2008). Conversely, preventing cpA from detecting changes in CO2 dramatically reduces attraction toward CO2 sources (Erdelyan et al., 2012,Turner et al., 2011).

    The role of human odor in host seeking is more complex since it is a blend of hundreds of volatiles from skin, sweat, and associated microbiota (Bernier et al., 2000,Dormont et al., 2013,Gallagher et al., 2008) (see for more references). ORNs in the antennae and palps express members of the Or and IR chemoreceptor families (Kwon et al., 2006,Lu et al., 2007,Pitts et al., 2011,Qiu et al., 2006,Syed and Leal, 2007) that respond to some skin odorants and are candidates for contributing to skin attraction (Carey et al., 2010,Wang et al., 2010). Other studies on antennal or maxillary palp sensilla have also identified activating odorants from skin (Ghaninia et al., 2008,Qiu et al., 2006,Syed and Leal, 2007). However, a causal relationship between activity of particular receptors or neuron classes and behavioral attraction has not been established as with the cpA neuron and CO2. Of the odorants that have been tested, a small number, such as lactic acid, ammonia, carboxylic acids, 1-octen-3-ol, and nonanal, increase mosquito attraction when presented together with CO2, but these are poor attractants by themselves (Njiru et al., 2006,Qiu et al., 2007,Syed and Leal, 2009), reviewed in Smallegange and Takken, 2010. Mosquitoes are nonetheless attracted to whole skin odor even in the absence of CO2 (Geier et al., 1999,Lacey and Cardé, 2011,Njiru et al., 2006,Schreck et al., 1981,Smallegange et al., 2010a). Intriguingly, mosquitoes that lack the coreceptor orco, and so lack functional Or receptors, are still attracted strongly to human skin odor with CO2 (DeGennaro et al., 2013), suggesting that other receptors may also play a role in skin attraction.

    Here, we show that the CO2-sensitive, Gr-expressing cpA olfactory neurons on the maxillary palps of mosquitoes are also sensitive detectors of human skin odor, a function conserved in A. aegypti and A. gambiae. We use a novel chemical strategy to selectively knock down cpA responses to skin odor and demonstrate that this neuronal pathway is also important for attraction to skin odor in a wind tunnel. The role of this neuron class in host-seeking behavior toward both CO2 and skin odor establishes it as the key target for behavioral intervention. We screen ∼0.5 million compounds in silico to identify new receptor ligands that modify mosquito behavior, including a cpA antagonist that reduces attraction to skin and an agonist that lures mosquitoes as effectively as CO2. We demonstrate inDrosophila melanogaster that neuronal response and aversive behavior to a structurally diverse panel of odorants depends on the highly conserved CO2receptor. Our analysis of the CO2 neuron ligand space provides a foundation for understanding mosquito host-seeking behavior and the chemical basis of host attractiveness and identifies odors that are safe, pleasant, and affordable for immediate use in mosquito control.

    Issued on: http://www.cell.com/

     
  15. Film of cancer foundation.

    Every patient is so happy to see fluffy hair style again, indeed, it is the best gift ever!

    Read More